Six common photosensitizing drugs should be sunscreen after use

[ China Pharmaceutical Network Health Health ] The occurrence of photosensitivity is related to physical fitness, and individual differences are large. After taking or injecting photosensitizing drugs, outdoor activities are carried out at the same time. The skin that has been exposed to the sun may be abnormal. Light redness and itching may occur, and severe cases may have acne, blisters, etc., and a few people may have fever, dizziness, etc. Systemic symptoms, and the greater the amount of medication taken, the longer the outdoor time, the heavier the symptoms. The US Health magazine website recently counted six common photosensitizing drugs.

(Six common photosensitizing drugs should be used after sunscreen. Source: Baidu Pictures)

1. Retinoids for the treatment of acne. Retinoic acid, also known as retinoic acid, is a metabolic intermediate of vitamin A in the body and can be used to treat skin diseases such as acne, psoriasis and ichthyosis. Studies have found that retinoids can induce photosensitivity reactions, and patients may have adverse reactions such as dry skin and peeling. In addition, skin care products containing salicylic acid and benzoyl peroxide may also have these side effects, and special care must be taken.

2. Part of the antibacterial medicine. The common quinolone (Shaxing) antibacterial agents have a high incidence of photosensitivity, and the drugs are levofloxacin and ciprofloxacin. Also, tetracycline, chloramphenicol, and sulfamethoxazole, which treats tuberculosis, may also cause photosensitivity. These drugs are not only photosensitizing, but may also cause sunburn after taking them.

3. Non-steroidal anti-inflammatory drugs. For example, naproxen and the like. These drugs may also cause photosensitivity reactions and should be used with care.

4. Antiallergic drugs. Antiallergic drugs such as beramamine and chlorpheniramine are also a major risk factor for photosensitivity. For some patients, taking these drugs can reduce the ability to sweat and cause the body to dissipate heat in a timely manner, causing high fever.

5. Part of the antidepressant. Patients taking antidepressants such as chlorpromazine hydrochloride should also pay attention to sun protection. Clinical studies have found that long-term use of such drugs can show grayish blue or purple pigmentation in the body's light. In addition, taking tricyclic antidepressants in hot weather will affect the brain's body temperature regulation of heat stroke, and it is prone to heat stroke in severe cases.

6. Vitamins. Niacin (vitamin B3), which is used to treat high cholesterol, causes skin reactions and may cause the person to be sensitive to light. There are also many over-the-counter herbs that are phototoxic, such as St. John's Wort.

There are also transdermal patches for the need to avoid sun exposure after medication. Intense sun exposure amplifies the effects of transdermal patches (such as the analgesic fentanyl and blood pressure-reducing clonidine), which deliver drugs directly through the skin. When sunburned, the blood vessels on the surface of the skin will expand, resulting in an increase in drug absorption.

When taking the above drugs, you should pay attention to the application of sunscreen lotion or parasols to avoid direct photoreaction.

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