On February 15th, an article was published in PLOS one magazine, which showed us a new method of ultra-sensitive and ultra-fast HIV detection. This design can be tested in a week after infection, and the total duration is 4 hours and 45 minutes, and the results can be obtained on the test day.
Early detection of HIV infection is a key point in stopping the spread of AIDS and an important way to improve the effectiveness of antiretroviral treatment.
The Nucleic Acid Amplification Test (NAAT) has become the gold standard for the discovery of low concentrations of viruses in blood samples. However, such methods have technical requirements and are costly for developing countries.
Immunoassays are relatively more affordable and more suitable for immediate diagnosis. However, many of these methods are currently less sensitive.
What are the advantages of the new method we are going to introduce today? Let's take a look at its structure and principles.
Biochip
First, as a biosensor, its volume is small.
The new technology uses a "sandwich"-like structure that combines silicon micromechanical structures with gold nanoparticles and antibodies.
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