Smoking can induce uroepithelial neoplasia

A study published recently in the British Journal of International Urology shows that smoking can significantly increase the risk of severe uroepithelial neoplasia in people, especially women, and the risk of death increases with smoking.

Although the biological mechanism behind gender differences is not yet clear, studies have shown that medical personnel and the general public should do a good job in preventing smoking and quitting smoking to help people, especially women, actively prevent the fatality of bladder cancer, fallopian tube cancer, and kidney cancer. cancer.

To assess the gender impact of smoking habits and the long-term effects of smoking on the health of urothelial tumor patients, researchers led by Dr. Shahrokh Shariat of Cornell University School of Medicine conducted a study of 864 patients from five international institutions. Of these, 553 were males and 311 were females. All of these patients received urothelial surgery.

The study found that female smokers are more likely to have cancer recurrence than male smokers; for women with long-term heavy smoking, their cancer recurrence rate and mortality are 70% and 100% higher than those of men, respectively; while smoking Weight, duration, and degree of accumulation are only associated with cancer recurrence and death in female patients; for women who quit smoking for more than 10 years, both women and men, the risk of dying from cancer returns to the risk of non-smokers Level.

Dr. Shariat said: “The biological and clinical effects of smoking appear to be different in women and men, and more studies are needed to explore the causes of this difference. In addition, smoking prevention and smoking cessation behaviors targeting different genders will be It will have a major impact on uroepithelial neoplasia."