Anhan NaviCam "Magnetic Control Capsule Gastroscope" robot is known as "a revolutionary innovation in the examination of digestive tract diseases and endoscopic development in the 21st century" and won the "China Top Ten Medical Progress Awards". Up to now, the product has been clinically applied in more than 100 top three hospitals and more than 500 physical examination centers in 29 provinces and cities nationwide.
In 2014, Anhan's “Magnetic Control Capsule Gastroscope†robot received CE certification from the European Union and was included in the UK's list of innovative medical services. This product is also widely used in some European countries.
Recently, the Arterial Network interviewed Dr. Yan Dandan, Vice President of Anhan Medical. Yan Dandan shared with us the history of Anhan, and the main product of Anhan, Anhan NaviCam, "Magnetic Control Capsule Gastroscope" robot. R&D, application and marketization processes.
Starting from the clinical pain point, cutting into the market with medical robots as the entrance
Anhan is mainly engaged in disease detection and analysis in the field of digestive tract. From 2009 to now, the team has spent almost 9 years completely researching and commercializing the world's only capsule gastroscope robots that can perform accurate stomach examinations.
Anhan's "magnetron capsule gastroscope" robot realizes the dream of "no intubation to make a gastroscope". Just swallow a capsule-sized capsule gastroscope with water, and in 15 minutes, you can complete a gastroscopy with no pain, no invasiveness, no anesthesia, no dead angle, no cross infection. The examination is comfortable, accurate and safe. It has become the clinical recommendation standard for gastroscopy in China, and it is of great significance for early screening of gastric cancer in China.
Why is Anhan considering such a product?
Yan Dandan tells us that digestive tract disease is a disease that is high in the world, and gastric cancer ranks fourth in the world's cancer incidence rate. China is even more than ten people and nine stomachs. The digestive tract disease is very high, every year. There are about 680,000 cases of gastric cancer.
If the disease of gastric cancer is discovered early, almost 90% of it can be cured. It is only necessary to use a traditional gastroscope to make a mucosal peeling under a gastroscope. However, about 90% of China's gastric cancers are found in the late stage, and the survival rate is less than 30%.
Japan and South Korea are both in Asia, and the genetic factors of our country and their population, including eating habits, are very similar. In both countries, gastric cancer is also a high-risk disease, but Japan and South Korea have been forced by the state to conduct gastric cancer screening very early in the country. After so many years of early gastric cancer screening, their current early diagnosis rate can reach 50%. Above, the 5-year survival rate can reach more than 60%, which increases the patient's life by 10-20 years.
So why is China not conducting a large-scale screening of gastric cancer? Yan Dandan explained that the first digestive tract disease is not sensitive. If the country does not conduct forced screening, when the stomach is uncomfortable, few people think that they should do a stomach cancer check. And even if many stomach cancers are very serious, there is no obvious subjective feeling.
In addition, the traditional gastroscope is very painful, often making patients "distracted." The discomfort that traditional gastroscopes bring to patients is the main reason why many patients are reluctant to do stomach examinations. Yan Dandan also tried to enter the word "gastroscope" on Baidu to query. The first thing that popped up was everyone's question: Is the traditional gastroscopy painful? Is anesthesia harmful?
Second, if compared with the 10% screening ratio in Japan and South Korea, China does not have so many doctor resources to support a wide range of gastrointestinal diseases.
According to statistics, only 6218 medical institutions in China can carry out digestive endoscopy. And because it is a traditional type of intubation, the risk is very high and must be performed by a senior doctor.
However, there are only more than 20,000 doctors in China who can perform intubation gastroscopy of the digestive tract. Even if the doctor works at full capacity every year, only more than 22 million gastroscopy can be completed. If you go to the top three hospitals to make a gastroscopy, it may take a month or two, or even three months.
Based on these clinical pain points, Anhan also began to think about how to turn it into a small robot and check it by oral capsules. The market for this disease is very broad. Anhan first thought of cutting through the entrance of medical robots, expanding from a disease inspection to the entire physical examination screening market, and further expanding the market space.
After deciding to use the capsule gastroscope product, the first problem Anhan faced was how to carry out precise control.
The stomach is a very large hollow organ. If it is not controlled, it means that only a wireless camera is put in. There is no way to make accurate observations, which will lose its clinical significance. Therefore, Anhan decided to make the capsule gastroscope an active, controllable robot product.
There are several control methods for the robot. If the handheld external magnet control method is adopted, there is no way to carry out some complicated synchronous joint control due to its working distance and human operation accuracy. Magnetic resonance imaging also creates problems with magnetic field instability, and its power consumption is very high, resulting in high costs for power and cooling.
After continuous experimentation, Anhan finally decided to adopt a magnetic field with an external mechanical arm to perform precise multi-dimensional rotational movement and adaptive matching of the magnetic field. After thousands of trials, I finally achieved success. Yan Dandan said that no matter which product, Anhan has carried out a lot of preliminary tests.
Speak with data, from point to face
Anhan's "Magnetic Capsule Gastroscope" robot is a subversive innovation compared to traditional gastroscopes. Yan Dandan said that it is a very good example of "medical impossible triangle".
In the “Medical Impossibility Triangleâ€, the accessibility of medical resources under the existing system, the quality of medical services and the overall reduction of medical costs are a triangle problem that cannot be solved. The only way is to introduce a new technology increment to cause an expansion of the production network.
Anhan's "Magnetic Capsule Gastroscope" robot is such a technological advancement that it has made a breakthrough in the size from 1 meter to 27 mm, making it a robot close to the size of clinical oral capsules. This is a very striking contrast, and unintubated is a very low-risk operation that separates the doctor's diagnosis from the operation and addresses the limitations of medical resources.
So how does the accuracy of magnetic capsule capsule scanning compare with traditional gastroscope? Anhan insisted on answering this question by means of data. They selected five top-ranking top three hospitals in different regions of the country, including Shanghai Changhai Hospital, Beijing 301 Hospital, and Guangzhou Nanfang Hospital. They were led by Changhai Hospital and made 350 cases of magnetic capsule capsules and traditional Double-blind controlled trial of gastroscope.
The patient first performed Anhan's capsule gastroscopy, and then a different doctor performed a traditional gastroscopy, and then the results were compared. Results The control was chosen for focal lesions, because diffuse lesions were found throughout the stomach and were very easy to see. The comparison shows that compared with the traditional gastroscope, the accuracy of the Anhan capsule gastroscope inspection results reached 93.4%. The conclusion is that the Anhan magnetic capsule capsule has the same accuracy as the traditional gastroscope and can be used for screening gastric cancer.
Solving the problem of accuracy, Anhan encountered a second question: Can the magnetically controlled capsule gastroscope be screened for a large population?
For this problem, Anhan also chose to speak with data. They selected 3,822 patients from 99 medical centers with an average age of 44.8 years. By using a magnetically controlled capsule gastroscope, two thousandths of an asymptomatic population screened for gastric cancer.
The accuracy of Anhan's “Magnetic Control Capsule Gastroscope†robot has been recognized by the international academic community. In September 2016, the cover article "Comparative accuracy of magnetic capsule capsule and electronic gastroscope for diagnosis of gastric diseases" was published in the international academic journal "CGH" for digestive diseases and liver diseases. The paper deals with magnetic capsule capsule gastroscope and electronic gastroscope in stomach disease. The diagnostic accuracy was systematically compared. The results showed that Anhan's “Magnetic Control Capsule Gastroscope†robot has extremely high accuracy and the results are consistent with the “Gold Standard†electronic gastroscope.
Anhan is not limited to these points, they extend the application of magnetron capsule gastroscope robots to the surface through the Internet and artificial intelligence.
Anhan empowered grassroots doctors through the medical union, from the grassroots to the physical examination center, to the community hospital, to the top three hospitals, forming the entire medical structure. Quality control, including two-way referrals, is done within the pathway of the medical association.
At present, Shandong, Tianjin, Fujian and other places have established a medical association with Anhan "magnetic control capsule gastroscope" robot as the link, and established the "Magnetic Control Capsule Gastroscope Collaboration Center" to build a strict medical quality control system. Conduct screening for digestive tract tumors. Through the medical link, Anhan hopes to access more primary medical institutions to empower the grassroots.
The Internet is the most efficient. Anhan connects all inspectors, inspection agencies, and doctors on the cloud platform to share information through the platform. Whenever and wherever, as long as there is a network, doctors can remotely diagnose and consult the inspection data. Only one technician is required to operate locally.
Anhan also further liberated doctor resources through artificial intelligence to solve the problem of reading. Through artificial intelligence, the magnetic capsule capsule gastroscope robot can perform real-time diagnosis, and can perform automatic cruise inspection like a drone, and also focus on the lesion site without missing any lesions. After the small intestine is checked, it will be discharged with the body excretion, used once, no longer recycled, and there is no risk of cross-infection.
In order to expand the scope of application, Anhan has also established a quality control and training system for the entire process. In the traditional sense, the whole process refers simply from production to circulation, but Anhan capsule robot also includes all aspects from production to personnel training to operation inspection to data processing to expert reading to ensure that all aspects of inspection are done. QC.
In addition, Yan Dandan told us that Anhan's products are manufactured by self-built production lines, and the automation equipment on the production line is also independently developed. The Hubei production line has also been rated as a demonstration base for intelligent manufacturing in Hubei Province.
Led by the Chinese Medical Doctor Association, Anhan established the Capsule Gastroscope Training Academy. Operators can easily master the entire operating technology after a week or so of training, greatly improving efficiency.
Yan Dandan said that the current medical industry is constantly referring to artificial intelligence and big data. For Anhan, these technologies actually solve the clinical needs in the process of large-scale census.
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