Tiletamine Hydrochloride CAS 14176-50-2 for General Anesthesia Drugs Pain Killer

 

Baisc infomations of Tiletamin hydrochloride :

What is Tiletamine hydrochloride?
Tiletamine hydrochloride is a rapid-acting anesthetic combination as indicated:
In cats for restraint or for anesthesia combined with muscle relaxation.
In dogs for restraint and minor procedures of short duration (30 min. avg.) requiring mild to moderate analgesia.

Tiletamine is a dissociative anesthetic and pharmacologically classified as an NMDA receptor antagonist. It is related chemically to ketamine. Tiletamine hydrochloride exists as odorless white crystals.

Tiletamine hydrochloride Usages:
Tiletamine hydrochloride is used in veterinary medicine in the combination product Telazol (tiletamine/zolazepam, 50 mg/ml of each in 5 ml vial) as an injectable anesthetic for use in cats and dogs. It is sometimes used in combination with xylazine (Rompun) to tranquilize large mammals such as polar bears and wood bison. Telazol is the only commercially available tiletamine product in the United States. It is contraindicated in patients of an ASA score of III or greater and in animals with CNS signs, hyperthyroidism, cardiac disease, pancreatic or renal disease, pregnancy, glaucoma, or penetrating eye injuries.

Abuse of telazol has been documented. Animal studies have also shown that tiletamine produces rewarding and reinforcing effects. Tiletamine products are classified as Schedule III controlled substances in the United States.

Tiletamine hydrochloride dosage:
If used alone the dose for sedation is 0.5 to 2.0 mg/kg body weight depending on the species and desired level of effect. Uses and dose rates in combination with other drugs are found in Recommended route of administration is deep intramuscular injection.
 
ACTIONS: Tilzolan is a rapid-acting anesthetic combination of tiletamine hydrochloride and zolazepam hydrochloride. Tiletamine hydrochloride is a dissociative anesthetic agent whose pharmacologic action is characterized by profound analgesia, normal pharyngeal-laryngeal reflexes and cataleptoid anesthesia. The anesthetic state produced does not fit into the conventional classification of stages of anesthesia, but instead Tilzolan produces a state of unconsciousness which has been termed "dissociative" anesthesia in that it appears to selectively interrupt association pathways to the brain before producing somesthetic sensory blockade.


Cranial nerve and spinal reflexes remain active; however, these reflexes must not be confused with inadequate anesthesia. Analgesia results from apparent selective interruption of sensory inputs to the brain and usually persists after the anesthetic effect has subsided.

Tiletamine hydrochloride used for Cats:
In cats, the duration of effect of zolazepam exceeds that of tiletamine so that as the animal recovers there is a greater degree of tranquilization than anesthetization. There is a slight lowering of blood pressure during the first hour after injection. Heart rate and electrocardiogram readings are unaffected by Tilzolan (tiletamine HCl and zolazepam HCl). Arterial pO2 levels are decreased three minutes after injection but usually return to normal within 15 to 35 minutes.

Tiletamine hydrochloride used for Dogs: 
In dogs, the duration of effect of tiletamine exceeds that of zolazepam so there is a lesser degree of tranquilization than anesthetization in this species. The total effect of Tilzolan in dogs is of shorter duration than in cats.

Following administration of Tilzolan in dogs, a marked, persistent tachycardia occurs within two minutes following either 4.5 or 9 mg/lb (10 or 20 mg/kg) Tilzolan intramuscularly. Stroke volume decreases proportionately to the increased rate at the 4.5 mg/lb (10 mg/kg) dose, with little change in net cardiac output. There is an initial increase in systolic blood pressure, with a slight drop in pressure within five minutes. The systolic blood pressure remains at this decreased level throughout the duration of the anesthetic effect. Diastolic pressure increases throughout this same period. Following a 9 mg/lb (20 mg/kg) dose of Tilzolan in dogs, the relationship between stroke volume and heart rate is disproportionate, with a resultant substantial decrease in cardiac output. Contractility and mean blood pressure are decreased, indicating direct myocardial depression. Ventricular function is adequate. During surgical manipulations, tachycardia and hypertension may be observed, and may be brought on by sympathetic reaction to painful stimuli. Epinephrine is markedly less arrhythmogenic in animals under Tilzolan anesthesia than in those under halothane anesthesia.


Tiletamine hydrochloride COA:
 

Tiletamine hydrochloride Storage
-Keep the drug away from direct sunlight, heat and moisture. 
-Do not let the drug at the sight and reach of children.

Local anesthetics Products

Growth Hormne Peptides

 
 


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--------------------------------  Additional Information  -------------------------------
Place of origin : China
Brand : SMQ
Certificate : ISO9001:2008, KOSHER, GMP, SGS
Production capacity : 1000 Kilograms/Month

--------------------------------  Delivery Information  ---------------------------------
Packing : Foil bag/tin or as your request
Payment : T/T, Western Union, MoneyGram
Port : Shanghai, Shenzhen, Hongkong
Shipment method : EMS, DHL, FeDex, UPS, etc
Leading  time : Within 24 hours after payment
Delivery time : Within 6 business days after payment (door to door service)
--------------------------------  Our Competitive Advantages  ---------------------------
1.Please let me know the items you are looking for, quantity, and the destination country.
2. We send the detailed price of our product and offer the suitable shipping method for your reference.
3. You confirm the order and pay money 100% in advance and send us the detailed address.
4.We will pack your parcel and arrange to shipment according to your requirements
5.Once parcel is sent,I will offer you parcel's picture,tracking number and tracking website.
6.After you receiving parcel,we will offer you best after-sale.




 

 

Baisc infomations of Tiletamin hydrochloride :

What is Tiletamine hydrochloride?
Tiletamine hydrochloride is a rapid-acting anesthetic combination as indicated:
In cats for restraint or for anesthesia combined with muscle relaxation.
In dogs for restraint and minor procedures of short duration (30 min. avg.) requiring mild to moderate analgesia.

Tiletamine is a dissociative anesthetic and pharmacologically classified as an NMDA receptor antagonist. It is related chemically to ketamine. Tiletamine hydrochloride exists as odorless white crystals.

Tiletamine hydrochloride Usages:
Tiletamine hydrochloride is used in veterinary medicine in the combination product Telazol (tiletamine/zolazepam, 50 mg/ml of each in 5 ml vial) as an injectable anesthetic for use in cats and dogs. It is sometimes used in combination with xylazine (Rompun) to tranquilize large mammals such as polar bears and wood bison. Telazol is the only commercially available tiletamine product in the United States. It is contraindicated in patients of an ASA score of III or greater and in animals with CNS signs, hyperthyroidism, cardiac disease, pancreatic or renal disease, pregnancy, glaucoma, or penetrating eye injuries.

Abuse of telazol has been documented. Animal studies have also shown that tiletamine produces rewarding and reinforcing effects. Tiletamine products are classified as Schedule III controlled substances in the United States.

Tiletamine hydrochloride dosage:
If used alone the dose for sedation is 0.5 to 2.0 mg/kg body weight depending on the species and desired level of effect. Uses and dose rates in combination with other drugs are found in Recommended route of administration is deep intramuscular injection.
 
ACTIONS: Tilzolan is a rapid-acting anesthetic combination of tiletamine hydrochloride and zolazepam hydrochloride. Tiletamine hydrochloride is a dissociative anesthetic agent whose pharmacologic action is characterized by profound analgesia, normal pharyngeal-laryngeal reflexes and cataleptoid anesthesia. The anesthetic state produced does not fit into the conventional classification of stages of anesthesia, but instead Tilzolan produces a state of unconsciousness which has been termed "dissociative" anesthesia in that it appears to selectively interrupt association pathways to the brain before producing somesthetic sensory blockade.


Cranial nerve and spinal reflexes remain active; however, these reflexes must not be confused with inadequate anesthesia. Analgesia results from apparent selective interruption of sensory inputs to the brain and usually persists after the anesthetic effect has subsided.

Tiletamine hydrochloride used for Cats:
In cats, the duration of effect of zolazepam exceeds that of tiletamine so that as the animal recovers there is a greater degree of tranquilization than anesthetization. There is a slight lowering of blood pressure during the first hour after injection. Heart rate and electrocardiogram readings are unaffected by Tilzolan (tiletamine HCl and zolazepam HCl). Arterial pO2 levels are decreased three minutes after injection but usually return to normal within 15 to 35 minutes.

Tiletamine hydrochloride used for Dogs: 
In dogs, the duration of effect of tiletamine exceeds that of zolazepam so there is a lesser degree of tranquilization than anesthetization in this species. The total effect of Tilzolan in dogs is of shorter duration than in cats.

Following administration of Tilzolan in dogs, a marked, persistent tachycardia occurs within two minutes following either 4.5 or 9 mg/lb (10 or 20 mg/kg) Tilzolan intramuscularly. Stroke volume decreases proportionately to the increased rate at the 4.5 mg/lb (10 mg/kg) dose, with little change in net cardiac output. There is an initial increase in systolic blood pressure, with a slight drop in pressure within five minutes. The systolic blood pressure remains at this decreased level throughout the duration of the anesthetic effect. Diastolic pressure increases throughout this same period. Following a 9 mg/lb (20 mg/kg) dose of Tilzolan in dogs, the relationship between stroke volume and heart rate is disproportionate, with a resultant substantial decrease in cardiac output. Contractility and mean blood pressure are decreased, indicating direct myocardial depression. Ventricular function is adequate. During surgical manipulations, tachycardia and hypertension may be observed, and may be brought on by sympathetic reaction to painful stimuli. Epinephrine is markedly less arrhythmogenic in animals under Tilzolan anesthesia than in those under halothane anesthesia.


Tiletamine hydrochloride COA:
 

Tiletamine hydrochloride Storage
-Keep the drug away from direct sunlight, heat and moisture. 
-Do not let the drug at the sight and reach of children.

Local anesthetics Products

Growth Hormne Peptides

 
 


Related products
Bodybuilding Steroid Powder/Raw Material Hormone Powder/ Enhances Muscle Steroid Powder:

 
 
 
Epiandrosteron (CAS: 481-29-8)
DHE. A(Dehydroepiandrosteron) (CAS: 53-43-0)


 
 
Tadalafi(Ciali) (CAS: 171596-29-5)
Vardenafil (Levitr) (CAS: 224785-91-5)
 

Weight Loss Powder:
 
Phentermin Hydrochloride(CAS: 1197-21-3)
L(-)-Carnitine (CAS: 541-15-1)
Rimonabant (CAS: 158681-13-1)



Plant Extract
Tribulus extract (CAS No. 22153-44-2)
Trigonelline (CAS No. 535-83-1)
Curcumin (CAS No. 458-37-7)
Oat Extract (CAS No. 84012-26-0)
Tongkat Ali extract (CAS No. 84633-29-4)
Vitexin (CAS No. 3681-93-4)


--------------------------------  Additional Information  -------------------------------
Place of origin : China
Brand : SMQ
Certificate : ISO9001:2008, KOSHER, GMP, SGS
Production capacity : 1000 Kilograms/Month

--------------------------------  Delivery Information  ---------------------------------
Packing : Foil bag/tin or as your request
Payment : T/T, Western Union, MoneyGram
Port : Shanghai, Shenzhen, Hongkong
Shipment method : EMS, DHL, FeDex, UPS, etc
Leading  time : Within 24 hours after payment
Delivery time : Within 6 business days after payment (door to door service)
--------------------------------  Our Competitive Advantages  ---------------------------
1.Please let me know the items you are looking for, quantity, and the destination country.
2. We send the detailed price of our product and offer the suitable shipping method for your reference.
3. You confirm the order and pay money 100% in advance and send us the detailed address.
4.We will pack your parcel and arrange to shipment according to your requirements
5.Once parcel is sent,I will offer you parcel's picture,tracking number and tracking website.
6.After you receiving parcel,we will offer you best after-sale.




 

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